UK pharmaceutical investment competitiveness benchmark 2026: Green shoots, global competition, and the case for delivery

Annual Core Metrics Edition

  • UK competitive
  • UK semi-competitive
  • UK uncompetitive
  • Change in UK rank since 2025

General considerations

icon Talent & workforce

Level of expertise

Graduates with degrees in natural sciences, mathematics or statistics (%)

▼ 5
2023

Country rankings for Level of expertise.

  1. FR flag 8.47
  2. US flag 8.30
  3. DE flag 8.21
  4. CA flag 8.06
  5. IT flag 7.98
  6. GB flag 7.97
  7. IE flag 7.81
  8. CH flag 6.93
  9. SG flag 4.98
  10. ES flag 4.50
  11. BE flag 4.27

Ease of immigration

Costs for skilled worker visa (£)

-
2025

Country rankings for Ease of immigration.

  1. JP flag 21
  2. DE flag 170
  3. ES flag 172
  4. SG flag 209
  5. CN flag 248
  6. FR flag 276
  7. IT flag 278
  8. BE flag 442
  9. CA flag 675
  10. IE flag 850
  11. CH flag 956
  12. US flag 7829
  13. GB flag 12451
Political & economic stability

Political stability

Political stability (index)

▲ 1
2024

Country rankings for Political stability.

  1. SG flag 86.9
  2. JP flag 85.3
  3. CH flag 82.6
  4. IE flag 78.0
  5. CA flag 76.1
  6. IT flag 71.2
  7. GB flag 70.3
  8. DE flag 68.0
  9. BE flag 68.0
  10. ES flag 65.8
  11. US flag 64.3
  12. CN flag 63.3
  13. FR flag 61.8

Economic stability

Sovereign economic risk (index)

-
2026

Country rankings for Economic stability.

  1. CA flag AAA
  2. DE flag AAA
  3. SG flag AAA
  4. CH flag AAA
  5. US flag AA+
  6. IE flag AA+
  7. GB flag AA
  8. BE flag AA
  9. FR flag A+
  10. JP flag A+
  11. CN flag A+
  12. ES flag A+
  13. IT flag BBB+
IP protection

Length of additional patent-based protection

Maximum duration of additional patent-based protection [excluding extensions for paediatric research] (years)

-
Country patent office
2026

Country rankings for Length of additional patent-based protection.

  1. GB flag 5
  2. FR flag 5
  3. IT flag 5
  4. DE flag 5
  5. JP flag 5
  6. US flag 5
  7. CN flag 5
  8. ES flag 5
  9. SG flag 5
  10. IE flag 5
  11. CH flag 5
  12. BE flag 5
  13. CA flag 2

Length of data-based protection (synthetics)

Period of market exclusivity based on protection of regulatory data [excluding extensions for new indications] (years)

-
Country legislation
2026

Country rankings for Length of data-based protection (synthetics).

  1. GB flag 10
  2. FR flag 10
  3. IT flag 10
  4. DE flag 10
  5. ES flag 10
  6. IE flag 10
  7. CH flag 10
  8. BE flag 10
  9. CA flag 8
  10. JP flag 8
  11. CN flag 6
  12. US flag 5
  13. SG flag 5

Length of data-based protection (biologics)

Period of market exclusivity based on protection of regulatory data [excluding extensions for new indications] (years)

-
Country legislation
2026

Country rankings for Length of data-based protection (biologics).

  1. US flag 12
  2. GB flag 10
  3. FR flag 10
  4. IT flag 10
  5. DE flag 10
  6. ES flag 10
  7. IE flag 10
  8. CH flag 10
  9. BE flag 10
  10. CA flag 8
  11. JP flag 8
  12. CN flag 6
  13. SG flag 5
Patient access

Medicines availability

New medicines fully available compared with licence (%)

-
2021-2024

Country rankings for Medicines availability.

  1. DE flag 93
  2. IT flag 73
  3. CH flag 50
  4. BE flag 49
  5. GB flag 33
  6. ES flag 33
  7. FR flag 30
  8. IE flag 26

Medicines adoption

Median year 3 uptake of NICE-approved new medicines (days of therapy per capita)

-
ABPI (IQVIA)
2025

Country rankings for Medicines adoption.

  1. DE flag 5.5
  2. IT flag 4.7
  3. ES flag 4.5
  4. FR flag 2.9
  5. GB flag 2.3
Reimbursement

Medicines spend

Spending on new, innovative medicines per capita (% of GDP)

-
2023

Country rankings for Medicines spend.

  1. US flag 0.78
  2. ES flag 0.53
  3. IT flag 0.46
  4. JP flag 0.40
  5. DE flag 0.36
  6. CA flag 0.32
  7. FR flag 0.29
  8. GB flag 0.28

Clawback rate

Average clawback rate (% of revenue)

-
Country legislation
2026

Country rankings for Clawback rate.

  1. CA flag 0
  2. JP flag 0
  3. US flag 0
  4. CN flag 0
  5. SG flag 0
  6. CH flag 0
  7. FR flag 6.45
  8. IT flag 6.83
  9. DE flag 7
  10. ES flag 7.5
  11. BE flag 7.86
  12. IE flag 9
  13. GB flag 14.5
Regulatory environment

Marketing authorisation approval time

Median days to obtain marketing authorisation approval for new active substances

▲ 3
2025

Country rankings for Marketing authorisation approval time.

  1. JP flag 292
  2. US flag 322
  3. CA flag 369
  4. GB flag 378
  5. CH flag 413
  6. FR flag 448
  7. IT flag 448
  8. DE flag 448
  9. ES flag 448
  10. IE flag 448
  11. BE flag 448
Financial incentives

Research incentives

Implied tax subsidy rates on R&D expenditure for profitable large companies

-
2025

Country rankings for Research incentives.

  1. FR flag 0.36
  2. ES flag 0.33
  3. CN flag 0.32
  4. IE flag 0.27
  5. DE flag 0.22
  6. GB flag 0.18
  7. JP flag 0.17
  8. BE flag 0.16
  9. CA flag 0.14
  10. IT flag 0.09
  11. US flag 0.07
  12. CH flag -0.01

Research incentives

Statutory corporate income tax rates (%)

-
2025

Country rankings for Research incentives.

  1. IE flag 12.50
  2. SG flag 17.00
  3. CH flag 19.61
  4. GB flag 25.00
  5. CN flag 25.00
  6. ES flag 25.00
  7. BE flag 25.00
  8. US flag 25.57
  9. CA flag 25.98
  10. IT flag 27.81
  11. JP flag 29.74
  12. DE flag 30.06
  13. FR flag 36.13

Commercialisation incentives

Patent box, lowest possible effective tax rates (%)

▲ 1
2025

Country rankings for Commercialisation incentives.

  1. BE flag 3.75
  2. SG flag 5
  3. CH flag 8.23
  4. GB flag 10
  5. ES flag 10
  6. IE flag 10
  7. FR flag 14.45
Data & AI capabilities

AI infrastructure

Number of data centres

-
2025

Country rankings for AI infrastructure.

  1. US flag 5427
  2. DE flag 529
  3. GB flag 523
  4. CN flag 449
  5. CA flag 337
  6. FR flag 322
  7. JP flag 222
  8. IT flag 168

AI commercialisation

Number of newly funded AI companies

-
2025

Country rankings for AI commercialisation.

  1. US flag 1953
  2. GB flag 172
  3. CN flag 161
  4. DE flag 92
  5. FR flag 84
  6. CA flag 79
  7. JP flag 56
  8. SG flag 49
  9. IT flag 38
  10. CH flag 34
  11. ES flag 33

AI research ecosystem

Number of notable AI models (biology and medicine)

-
2025

Country rankings for AI research ecosystem.

  1. US flag 39
  2. GB flag 13
  3. CN flag 9
  4. DE flag 6
  5. CA flag 3
  6. FR flag 2
  7. JP flag 2

Pre-clinical research

Science base

Reputation

Number of top 100 universities for life sciences and medicine degrees

-
2026

Country rankings for Reputation.

  1. US flag 30
  2. GB flag 16
  3. CA flag 5
  4. CN flag 5
  5. DE flag 4
  6. FR flag 3
  7. IT flag 2
  8. JP flag 2
  9. ES flag 2
  10. SG flag 2
  11. CH flag 2
  12. BE flag 2
  13. IE flag 1

Quality of research output

Global share of most highly cited (top 1%) medical publications (%)

▼ 1
2024

Country rankings for Quality of research output.

  1. FR flag 1.9
  2. GB flag 1.8
  3. DE flag 1.7
  4. CA flag 1.7
  5. IT flag 1.7
  6. US flag 1.1
  7. CN flag 1.1
  8. JP flag 0.9

Quality of research output

Nature Index for high-quality research outputs in selected journals for health sciences

▼ 1
2025

Country rankings for Quality of research output.

  1. US flag 12247
  2. CN flag 8461
  3. GB flag 3407
  4. DE flag 2633
  5. CA flag 2011
  6. FR flag 1815
  7. IT flag 1434
  8. JP flag 1270
  9. ES flag 1252
  10. CH flag 1163
  11. BE flag 695
  12. SG flag 516
  13. IE flag 252

Research commercialisation

Number of biotechnology companies

-
2026

Country rankings for Research commercialisation.

  1. US flag 9066
  2. CN flag 2424
  3. GB flag 1606
  4. DE flag 1329
  5. CA flag 1126
  6. FR flag 959
  7. CH flag 794
  8. ES flag 580
  9. JP flag 549
  10. IT flag 467
  11. BE flag 332
  12. SG flag 211
  13. IE flag 143

Research commercialisation

Venture capital raised by biotechs (£ million)

-
BIA
2025

Country rankings for Research commercialisation.

  1. US flag 15515
  2. GB flag 1785
  3. CH flag 807
  4. FR flag 600
  5. DE flag 448
Research funding

Government funding

Government budget allocations for health R&D (% of GDP)

-
2024

Country rankings for Government funding.

  1. US flag 0.17
  2. GB flag 0.12
  3. IT flag 0.07
  4. CA flag 0.07
  5. ES flag 0.07
  6. JP flag 0.06
  7. DE flag 0.06
  8. FR flag 0.03
  9. BE flag 0.01
  10. IE flag 0.01
  11. CH flag 0.00
Research infrastructure

Government research

Expenditure on medical R&D performed by government (% of GDP)

-
2023

Country rankings for Government research.

  1. SG flag 0.14
  2. ES flag 0.09
  3. DE flag 0.04
  4. IT flag 0.04
  5. JP flag 0.03
  6. BE flag 0.02
  7. GB flag 0.01
  8. IE flag 0.01
  9. FR flag 0.00

Non-profit research

Expenditure on medical R&D performed by the private non-profit sector (% of GDP)

-
2023

Country rankings for Non-profit research.

  1. DE flag 0.07
  2. CH flag 0.04
  3. GB flag 0.04
  4. JP flag 0.04
  5. FR flag 0.04
  6. IT flag 0.02
  7. BE flag 0.02
  8. CA flag 0.01
  9. ES flag 0.00
  10. IE flag 0.00

University research

Expenditure on medical R&D performed by the higher education sector (% of GDP)

-
2023

Country rankings for University research.

  1. CH flag 0.19
  2. BE flag 0.17
  3. DE flag 0.13
  4. JP flag 0.13
  5. GB flag 0.09
  6. SG flag 0.08
  7. FR flag 0.07
  8. ES flag 0.07
  9. IE flag 0.05
  10. IT flag 0.05

Clinical research

Research infrastructure

Research capacity

Number of clinical trial sites per million population (thousands)

-
2024

Country rankings for Research capacity.

  1. CA flag 18.1
  2. DE flag 18.1
  3. BE flag 17.8
  4. CH flag 14.9
  5. IT flag 12.5
  6. ES flag 11.2
  7. JP flag 10.4
  8. GB flag 10.1
  9. IE flag 9.6
  10. FR flag 9.0
  11. US flag 8.6
  12. SG flag 6.3
  13. CN flag 1.0

Research intensity

Number of hospitals delivering over 100 industry clinical trials

-
2024

Country rankings for Research intensity.

  1. US flag 933
  2. JP flag 127
  3. GB flag 104
  4. IT flag 97
  5. DE flag 85
  6. CN flag 60
  7. CA flag 56
  8. ES flag 51
  9. FR flag 40
  10. BE flag 21
  11. CH flag 5
  12. IE flag 3
  13. SG flag 2
Standard of care

Medicines availability

New medicines fully available compared with licence (%)

-
2021-2024

Country rankings for Medicines availability.

  1. DE flag 93
  2. IT flag 73
  3. CH flag 50
  4. BE flag 49
  5. GB flag 33
  6. ES flag 33
  7. FR flag 30
  8. IE flag 26

Medicines adoption

Median year 3 uptake of NICE-approved new medicines (days of therapy per capita)

-
ABPI (IQVIA)
2025

Country rankings for Medicines adoption.

  1. DE flag 5.5
  2. IT flag 4.7
  3. ES flag 4.5
  4. FR flag 2.9
  5. GB flag 2.3
Approvals & contracting

Study set-up

Median days from clinical trial application to first patient, first dose

-
2023

Country rankings for Study set-up.

  1. US flag 174
  2. ES flag 239
  3. DE flag 250
  4. CA flag 252
  5. IT flag 285
  6. FR flag 287
  7. CH flag 300
  8. GB flag 338
Specialised infrastructure

Advanced therapies

Number of cell and gene therapy clinical trials initiated

-
2024

Country rankings for Advanced therapies.

  1. CN flag 346
  2. US flag 278
  3. GB flag 47
  4. ES flag 36
  5. DE flag 33
  6. FR flag 32
  7. CA flag 29
  8. JP flag 26
  9. IT flag 24
  10. BE flag 10
  11. CH flag 9
  12. SG flag 6
  13. IE flag 2
Patient enrolment

Scale of enrolment

Global share of patients recruited to a subset of commercial trials (%)

-
2023

Country rankings for Scale of enrolment.

  1. US flag 35.2
  2. ES flag 4.3
  3. DE flag 3.2
  4. CA flag 2.9
  5. GB flag 2.7
  6. FR flag 2.4
  7. IT flag 2.1
  8. CH flag 0.2

Manufacturing and distribution

Manufacturing infrastructure

Pharmaceutical manufacturing

Value of global exports of pharmaceutical products (£ billion)

-
2024

Country rankings for Pharmaceutical manufacturing.

  1. DE flag 102.9
  2. CH flag 102.1
  3. IE flag 93.5
  4. US flag 92.1
  5. BE flag 49.7
  6. CN flag 47.9
  7. IT flag 45.5
  8. FR flag 35.1
  9. GB flag 24.7
  10. ES flag 16.8
  11. JP flag 12.1
  12. CA flag 9.1
  13. SG flag 8.7

Pharmaceutical manufacturing

Share of global exports of pharmaceutical products (%)

-
2024

Country rankings for Pharmaceutical manufacturing.

  1. DE flag 13.50
  2. US flag 11.10
  3. CH flag 10.50
  4. IE flag 10.30
  5. IT flag 6.13
  6. BE flag 5.89
  7. FR flag 4.64
  8. GB flag 3.10
  9. ES flag 2.45
  10. CN flag 1.96
  11. SG flag 1.79
  12. JP flag 1.71
  13. CA flag 1.34

Availability of renewables

Share of total energy supply from renewable sources (%)

-
2025

Country rankings for Availability of renewables.

  1. CH flag 20.5
  2. IT flag 15.5
  3. DE flag 15.2
  4. GB flag 14.9
  5. CA flag 14.3
  6. ES flag 14.2
  7. CN flag 9.2
  8. FR flag 8.2
  9. JP flag 8.1
  10. BE flag 7.2
  11. US flag 7.2
  12. SG flag 0.4

Availability of renewables

Generation of energy from renewable sources (GW)

▼ 1
2025

Country rankings for Availability of renewables.

  1. CN flag 2258.0
  2. US flag 467.9
  3. DE flag 199.9
  4. JP flag 134.5
  5. CA flag 110.5
  6. ES flag 98.6
  7. FR flag 83.6
  8. IT flag 78.3
  9. GB flag 65.1
  10. CH flag 25.6
  11. BE flag 17.1
  12. IE flag 8.1
  13. SG flag 1.7
Planning & permits

Ease of obtaining approvals

Operational efficiency of establishing a business location (index)

-
2025

Country rankings for Ease of obtaining approvals.

  1. US flag 89.98
  2. SG flag 81.29
  3. IT flag 72.87
  4. CA flag 69.36
  5. GB flag 68.71
  6. ES flag 67.88
  7. IE flag 52.82
  8. BE flag 41.54
Running costs

Energy costs

Industrial electricity prices excluding taxes (pence per kWh)

-
2024

Country rankings for Energy costs.

  1. CA flag 6.55
  2. ES flag 11.39
  3. JP flag 11.82
  4. BE flag 12.26
  5. FR flag 12.82
  6. IT flag 14.65
  7. DE flag 15.08
  8. CH flag 20.56
  9. IE flag 22.72
  10. GB flag 24.91
Supply Chains

Ease of compliance

Time and cost to comply with export and import requirements (index)

-
2025

Country rankings for Ease of compliance.

  1. BE flag 78.81
  2. IE flag 71.37
  3. IT flag 70.96
  4. SG flag 67.67
  5. CA flag 66.61
  6. GB flag 60.82
  7. US flag 43.3

Trade infrastructure

Digital and physical trade infrastructure (index)

-
2025

Country rankings for Trade infrastructure.

  1. SG flag 46.25
  2. US flag 42.38
  3. CA flag 40
  4. IT flag 33.53
  5. GB flag 31.31
  6. IE flag 29.58
  7. BE flag 25.78
Specialised infrastructure

Cell therapy manufacturing

Share of global exports of cell therapy products (%)

-
2024

Country rankings for Cell therapy manufacturing.

  1. US flag 48.50
  2. CH flag 12.10
  3. DE flag 11.00
  4. GB flag 1.24
  5. ES flag 0.92
  6. IE flag 0.81
  7. FR flag 0.44
  8. IT flag 0.38
  9. BE flag 0.07
  10. CN flag 0.03
  11. SG flag 0.01
  12. JP flag 0.00
  13. CA flag 0.00

Headquarters and affiliates

Existing industry presence

Established industry

Number of pharmaceutical companies

-
2026

Country rankings for Established industry.

  1. CN flag 927
  2. US flag 403
  3. GB flag 120
  4. DE flag 119
  5. JP flag 119
  6. CA flag 95
  7. ES flag 87
  8. CH flag 85
  9. IT flag 83
  10. FR flag 75
  11. IE flag 55
  12. BE flag 37
  13. SG flag 25

Emerging industry

Number of biotechnology companies

-
2026

Country rankings for Emerging industry.

  1. US flag 9066
  2. CN flag 2424
  3. GB flag 1606
  4. DE flag 1329
  5. CA flag 1126
  6. FR flag 959
  7. CH flag 794
  8. ES flag 580
  9. JP flag 549
  10. IT flag 467
  11. BE flag 332
  12. SG flag 211
  13. IE flag 143
Commercial market

Medicines availability

New medicines fully available compared with licence (%)

-
2021-2024

Country rankings for Medicines availability.

  1. DE flag 93
  2. IT flag 73
  3. CH flag 50
  4. BE flag 49
  5. GB flag 33
  6. ES flag 33
  7. FR flag 30
  8. IE flag 26

Medicines adoption

Median year 3 uptake of NICE-approved new medicines (days of therapy per capita)

-
ABPI (IQVIA)
2025

Country rankings for Medicines adoption.

  1. DE flag 5.5
  2. IT flag 4.7
  3. ES flag 4.5
  4. FR flag 2.9
  5. GB flag 2.3

Last reviewed date: 05 August 2026

Next review date: 05 August 2029